Table 1.
Characteristics of the patients
| Total group | SCI (n = 23) | MCI (n = 47) | p | |
|---|---|---|---|---|
| Age (range 45–79), years | 61.7 (7.2) | 58.8 (7.2) | 63.1 (6.8) | 0.03 |
| Education (range 7–18), years | 12.5 (2.9) | 13.4 (2.8) | 12.1 (2.9) | 0.08 |
| Gender, n male | 35 (50%) | 10 (44%) | 25 (53%) | 0.45 |
| Handedness, n right | 66 (94%) | 23 (100%) | 43 (92%) | 0.15 |
| APOE-€4, n carriers | 33 (47%) | 13 (57%) | 20 (43%) | 0.32 |
| MMSE1 | 28.1 (1.4) | 29.0 (1.0) | 27.6 (1.3) | <0.001 |
| Word list memory (RAVLT) | 7.8 (4.1) | 10.0 (2.9) | 6.7 (4.1) | <0.001 |
| Visual memory (RCFT) | 13.0 (6.8) | 17.3 (6.7) | 10.9 (5.8) | <0.001 |
| Response inhibition (CWIT) | 75.6 (47.1) | 61.1 (11.5) | 82.5 (55.4) | 0.02 |
| Working memory (Letter-Number Sequencing) | 8.3 (2.2) | 9.1 (2.2) | 7.9 (2.2) | 0.04 |
| Memory complaints (range 0–4) | 2.4 (1.1) | 2.5 (1.1) | 2.3 (1.1) | 0.58 |
| Concentration complaints (range 0–4) | 1.9 (1.2) | 2.1 (1.2) | 1.8 (1.2) | 0.27 |
| SCL-90-R depressive symptoms | 0.9 (0.7) | 1.1 (0.8) | 0.8 (0.6) | 0.28 |
| GDS-15 depressive symptoms | 3.3 | 3.4 | 3.3 | 0.22 |
| Aβ42, ng/l | 842.2 (291.1) | 869.1 (264.0) | 829.1 (305.4) | 0.54 |
| Aβ42, n pathological | 15 (21%) | 3 (13%) | 12 (26%) | 0.35 |
| T-tau, ng/l | 344.8 (201.4) | 263.0 (81.9) | 384.9 (229.5) | 0.01 |
| T-tau, n pathological | 16 (23%) | 2 (9%) | 14 (30%) | 0.07 |
| P-tau, ng/l | 75.8 (30.1) | 65.8 (12.2) | 80.7 (34.9) | 0.06 |
| P-tau, n pathological | 24 (34%) | 3 (13%) | 21 (45%) | 0.02 |
Values are presented as means (±SD) unless indicated otherwise. Raw scores of all variables are presented. The comparison of gender, handedness, APOE-€4, and pathological levels of CSF biomarkers between the SCI and MCI groups was made with a χ2 test (Pearson χ2 test p value is shown). The independent-samples t test was used to compare the groups for the remaining variables. 1 MMSE: maximum score: 30.