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. Author manuscript; available in PMC: 2013 Oct 25.

Published in final edited form as: Lab Invest. 2012 Mar 12;92(5):713–723. doi: 10.1038/labinvest.2012.45

Fig. 2 — (A) Body weight was measured at weeks 0, 1, 3, and 6 of WT and Casp1^−/− mice on a 6-week CTL or MCD diet (n = 5-7 in each group). (B, C) Representative images of H&E and Oil red O staining (ORO) staining of liver tissue displays the severity of cellular injury, further investigated by: (D) hepatic triglyceride (TG) (n=4-5) and (E) serum alanine aminotransferase (ALT) levels (n=5-6). (F) RT PCR analysis of pro-inflammatory cytokine tumor necrosis factor (TNFα) (n = 3-4), (G) macrophage marker F4/80 (n=6-8) and CD11c (n=4-5) in liver of Casp1^−/− mice compared to WT mice. Results are expressed as mean ± S.E.M. * P < 0.05; ** P < 0.01; ***P < 0.001 compared to controls.

Fig. 2 — (A) Body weight was measured at weeks 0, 1, 3, and 6 of WT and Casp1^−/− mice on a 6-week CTL or MCD diet (n = 5-7 in each group). (B, C) Representative images of H&E and Oil red O staining (ORO) staining of liver tissue displays the severity of cellular injury, further investigated by: (D) hepatic triglyceride (TG) (n=4-5) and (E) serum alanine aminotransferase (ALT) levels (n=5-6). (F) RT PCR analysis of pro-inflammatory cytokine tumor necrosis factor (TNFα) (n = 3-4), (G) macrophage marker F4/80 (n=6-8) and CD11c (n=4-5) in liver of Casp1^−/− mice compared to WT mice. Results are expressed as mean ± S.E.M. * P < 0.05; ** P < 0.01; ***P < 0.001 compared to controls.