Figure 3. Effect of Tenofovir on nucleotidase biological activity in activated CD4⁺ T cells and macrophages.

5’-Nucleotidase biological activity was measured (see methods section) in activated CD4⁺ T cells (A) and in macrophages (B) after 24 and 48hr with 1mg/ml of TFV treatment. Values are expressed as milli-Enzyme Units (mEU) per one million cells. Bars represent mean ± SEM from 5 separate experiments with different donors. *P<0.05 **P<0.01.