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. 2013 Oct 25;8(10):e78814. doi: 10.1371/journal.pone.0078814

Figure 6. Effect of TFV on the secretion of MIP3α, IL-8 and TNFα by macrophages, DCs and resting and activated CD4+ T cells.

Figure 6

Macrophages, DCs were treated with 1mg/ml of TFV for 12, 24 and 48hr and resting and activated CD4+ T cells were treated with TFV for 24 and 48hr. Secretion of MIP3α, IL-8 and TNFα was analyzed from culture supernatants by an enzyme-linked immunosorbent assay. Bars represent mean ± SEM from 3-4 independent experiments with different donors. *P<0.05 **P<0.01. A) secretion of MIP3α, IL-8 and TNFα from macrophages (B) secretion of IL-8 and TNFα from DCs. (C) secretion of IL-8 from resting CD4+ T cells. (D) secretion of IL-8 from activated CD4+ T cells.