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. 2013 Oct 25;8(10):e77994. doi: 10.1371/journal.pone.0077994

Figure 3. HPV16 E2 and Brd4 interact on chromatin in interphase and mitotic cells.

Figure 3

(A) C33A cells were co-transfected with VN-Brd4 and VC-16E2 BiFC constructs. Forty-eight hours post-transfection, cells were fixed and stained with anti-FLAG antibody (red) and DAPI. Merge 1 is a merge of the BIFC and DAPI panels and Merge 2 is a merge of BIFC, FLAG and DAPI panels. (B) C33A cells were co-transfected with Venus N and VC-16E2 BiFC constructs. Forty-eight hours post-transfection, the cells were stained with anti-FLAG antibody (red) and DAPI. Bar, 5 μm.