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. 2013 Oct 25;8(10):e78552. doi: 10.1371/journal.pone.0078552

Table 4. Univariate analysis for factors associated with HMLN metastasis in 129 PET/CT negative patients.

Variable Pathologically positive Pathologically negative P-value
Sex
Male 9 59
Female 8 54 0.929
Age
≦65 14 75
>65 3 37 0.201
Smoking status
Never smoker 11 62
Smoker 6 50 0.469
Concurrent lung disease or diabetes
Yes 8 9
Never 9 103 0.000
Location of the tumor
Central 5 16
Non-central 12 96 0.115
Lobar distribution
Upper or middle lobe 10 79
Lower lobe 7 33 0.331
Right or left lung distribution
Right lung 8 78
Left lung 9 34 0.066
Histopathological type
Adenocarcinoma 9 98
Non-adenocarcinoma 8 14 0.000
Differentiated degree
High 1 25
Medium 10 63
Lower 6 24 0.200
Pleural invasion
Yes 11 46
No 6 66 0.067
Tumor size
≦3cm 10 81
>3cm 7 31 0.255
SUVmax of primary tumor
≦4.0 3 58
>4.0 14 54 0.009