Table 3. Relation of disease-associated CSF microRNAs with cardinal symptoms in FM.
Pain threshold | FIQ pain | FIQ fatigue | MFIGF | |
---|---|---|---|---|
miR-21-5p | rs=-0.382 | rs=0.018 | rs=-0.103 | rs=0.138 |
p=0.276 | p=0.960 | p=0.776 | p=0.704 | |
n=10 | n=10 | n=10 | n=10 | |
miR-145-5p | rs=-0.115 | rs=0.709 | rs=0.687 | rs=0.276 |
p=0.751 | p=0.022 | p=0.028 | p=0.440 | |
n=10 | n=10 | n=10 | n=10 | |
miR-29a-3p | rs=-0.298 | rs=-0.055 | rs=-0.192 | rs=0.277 |
p=0.403 | p=0.881 | p=0.595 | p=0.439 | |
n=10 | n=10 | n=10 | n=10 | |
miR-99b-5p | rs=-0.553 | rs=-0.237 | rs=0.052 | rs=0.145 |
p=0.097 | p=0.510 | p=0.887 | p=0.690 | |
n=10 | n=10 | n=10 | n=10 | |
miR-125b-5p | rs=0.103 | rs=0.201 | rs=0.174 | rs=0.258 |
p=0.776 | p=0.578 | p=0.631 | p=0.472 | |
n=10 | n=10 | n=10 | n=10 | |
miR-23a-3p | rs=0.018 | rs=-0.103 | rs=0.036 | rs=0.088 |
p=0.960 | p=0.777 | p=0.920 | p=0.809 | |
n=10 | n=10 | n=10 | n=10 | |
miR-23b-3p | rs=-0.164 | rs=-0.285 | rs=0.055 | rs=0.32 |
p=0.651 | p=0.425 | p=0.881 | p=0.367 | |
n=10 | n=10 | n=10 | n=10 | |
miR-195-5p | rs=-0.370 | rs=-0.018 | rs=0.395 | rs=0.464 |
p=0.293 | p=0.960 | p=0.258 | p=0.177 | |
n=10 | n=10 | n=10 | n=10 | |
miR-223-3p | rs=-0.286 | rs=-0.310 | rs=0.137 | rs=0.447 |
p=0.424 | p=0.383 | p=0.705 | p=0.196 | |
n=10 | n=10 | n=10 | n=10 |
Spearmans rho (rs) of miRNA relative expression levels vs. symptom severity levels , two-tailed significance (p , and number of subjects (n) are presented.