Figure 4. Effects of BK B2 receptor antagonist and eNOS inhibitor on the protective effect of BK against H9C2 cells senescence.
Senescence was measured as the number of sa-β-gal–positive cells 3 days after treatment with H2O2. A, effect of BK B2 receptor antagonist HOE-140 on the protective effect of BK against H9C2 cells senescence. B, effect of L-NAME on the protective effect of BK against H9C2 cells senescence. Bars represent means ±SEM (*P<0.05 vs control; # P<0.05 vs H2O2; & P<0.05 vs H2O2+BK; n = 6).