Table 3.

Results of k_α, P_α, and J_α for folding tube α, determined from studying a simple folding model (Fig. S13) (neglecting the small intermediate state population).

	kα	Pα	Jα
General	$$\frac{{\text{J}}_{\mathrm{\alpha }}}{{\text{P}}_{\mathrm{\alpha }}}$$	$\frac{\sum _{\text{i}\in \text{U}}\text{t}(\text{i}\mid \mathrm{\alpha })}{{\text{T}}_{\text{total}}}$	$\sum _{\begin{array}{l}\text{i}\in \text{U},\text{j}\notin \text{U},\\ \text{j}\in \mathrm{\alpha }\end{array}}{\text{k}}_{\text{ij}}{\text{p}}_{\text{i}}^{\text{eq}}{\text{p}}_{\text{j}}^{\text{fold}}$
Fast U-State mixing (funneled folding landscape)	$$\frac{{\text{J}}_{\text{total}}}{{\text{P}}_{\text{total},\text{U}}^{\text{eq}}}$$	$$\frac{{\text{J}}_{\mathrm{\alpha }}}{{\text{J}}_{\text{total}}}{\text{P}}_{\text{total},\text{U}}^{\text{eq}}$$
Slow U-state mixing (hub folding landscape)	k13	${\text{p}}_{\text{1}}^{\text{eq}}$	${\text{k}}_{\text{13}}{\text{p}}_{\text{1}}^{\text{eq}}$
	k24	${\text{p}}_{\text{2}}^{\text{eq}}$	${\text{k}}_{\text{24}}{\text{p}}_{\text{2}}^{\text{eq}}$