Table 1. Patient Demographics.
Clinical Features of 23 patients with Sickle Cell Disease and acute VOC
| Feature | Number (%) |
|---|---|
|
| |
| Males: | 7 (30%) |
|
| |
| Mean Age (standard deviation) | 34.3 (7.96) |
|
| |
| Number of patients with SS/SC/ST | 22/1/0 |
|
| |
| Deaths | 1 (4%) |
|
| |
| Race | |
| African American | 10 (44%) |
| African | 7 (30%) |
| Hispanic/Latino | 6 (26%) |
|
| |
| Number of Patients with Liver Biopsy | 15 (65%) |
| Ishak Fibrosis Score 0–2 | 14 (93%) |
| Ishak Fibrosis Score 3–4 | 1 (7%) |
| Ishak Fibrosis Score 5–6 | 0 (0%) |
|
| |
| Liver Biopsy Features | Median (Range) |
|
| |
| HAI Total Inflammation (0–18) | 3.0 (0–8) |
|
| |
| Ishak Fibrosis (0–6) | 0 (0–3) |
|
| |
| Iron Score (0–4) | 3.0 (1–4) |
|
| |
| Liver Iron Concentration (normal: 200–2400 mcg/g dry weight) | 6943 (1907–36416) |
|
| |
| Deugnier Score | 28 (10–46) |
Abbreviations: VOC, vaso-occlusive crisis; HAI, Histologic Activity Index