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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Pain. 2013 Aug 8;154(11):10.1016/j.pain.2013.07.041. doi: 10.1016/j.pain.2013.07.041

Figure 3.

Figure 3

Hyperalgesic effect of Taxol in mice at 46 °C. A. Mice (N=16) received a cumulative 2 mg/kg dose of Taxol and were tested in a thermal operant system as described in the methods section. A * indicates p<0.05 and a ** indicates p<0.01 for week 3 and week 4 respectively in a Repeated Measures One-Way ANOVA followed by Dunnett’s test. B. Mice (N=8) received vehicle for Taxol and tested in the same device. There was no significant change in behavior at 46 °C for the vehicle group as evidenced by P>0.05 in a One-Way Repeated Measures ANOVA followed by Dunnett’s test. C and D. Thermal operant response at 37 °C for the above Taxol receiving group (N=16) and vehicle group (N=8) with a P>0.05 for both groups indicating no significant change in behavior at non-nociceptive temperature.