Thrombin15
|
Increase |
Formation of stress fibers to subsequently increase cell contraction |
Histamine16
|
Increase |
Increased intracellular Ca++ and Myosin Light Chain Kinase(MLCK) induced contraction |
Hydrogen Peroxide (H202)17
|
Increase |
RhoA activation, MLCK induced contraction |
Y276328
|
Decrease |
Cytoskeletal relaxation via Rho inhibition |
Sphingosine-1phosphate (S1P)18
|
Decrease |
Cadherin reorganization and cytoskeletal relaxation. |
Hepatocyte Growth Factor (HGF)19
|
Decrease |
Rac/Rho mediated cytoskeletal relaxation |