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. 2013 Oct 23;8(10):e78480. doi: 10.1371/journal.pone.0078480

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© 2013 Mills et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The fold-change of the genes was relative to their expression in WM. Those genes with a negative fold-change were up-regulated in GM (down-regulated in WM) and those genes with a positive fold-change were up-regulated in WM (down-regulated in GM). Genes that were statistically significant (q-value<0.05) are shown in red and were listed in Table S1. This figure demonstrates that a larger number of genes were significantly up-regulated in GM (1218) than were up-regulated in WM (434). Overall there was a greater spread of data for the genes that are up-regulated in GM.