Fig. 2.

Astrocytic dnSNARE expression attenuates behavioral consequences of epilepsy. (A and B) Representative 30 min of track plots of control no-SE and SE-experienced WT (A) and dnSNARE mice (B) placed in the open field 8 mo after pilocarpine treatment. (C) The average duration of time stopped over the 30-min test period was increased in SE WT mice but not in SE dnSNARE mice (WT no-SE, n = 8; WT SE, n = 7; dnSNARE no-SE, n = 7; dnSNARE SE, n = 8; ANOVA followed by post hoc test, *P < 0.05, WT SE vs. WT no-SE). (D) Line graph shows duration of time stopped in 1-min bins over the 30-min test period.