Fig. 2.

Structural repeat in AvrM. (A) The structures of AvrM contain two four-helical repeats (light blue and green) with similar folds. (B) Superposition of the two AvrM repeats showing the conserved fold [generated by using SSM (37)]. (C and D) Conserved hydrophobic residues stabilize the overall fold of the two repeats. (C) Ribbon diagram of repeat 1 (light blue) and 2 (green) in avrM with the hydrophobic residues highlighted in wireframe. (D) Structure-based sequence alignment of the two repeats. The residues in the ribbon diagrams and in the sequence alignment are numbered according to the avrM sequence.