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. 2013 Oct 7;110(43):E4059–E4068. doi: 10.1073/pnas.1312393110

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Fig. 1. — (A) Orientational states of the MyoV head with respect to its lever arm. For clarity, only one leg of the two-legged motor is shown, although the states are the same for both legs. (Left) Pr. (Middle) Po. For each state, the relaxed orientation (in the absence of tension on the lever arm end) is marked by a dashed red line. (Right) Po state with backward tension on the arm end, causing the lever arm to bend backward away from its relaxed direction. (B) Coarse-grained polymer representation of MyoV. (C) Schematic view of four MyoV kinetic pathways. For simplicity, the nucleotide-free state, following ADP release from the TH and before ATP binding, is not shown. (D) Probability of each kinetic pathway as a function of backward force F (with ) calculated from the theory using the parameter set in Table 1.

Inline graphic — (A) Orientational states of the MyoV head with respect to its lever arm. For clarity, only one leg of the two-legged motor is shown, although the states are the same for both legs. (Left) Pr. (Middle) Po. For each state, the relaxed orientation (in the absence of tension on the lever arm end) is marked by a dashed red line. (Right) Po state with backward tension on the arm end, causing the lever arm to bend backward away from its relaxed direction. (B) Coarse-grained polymer representation of MyoV. (C) Schematic view of four MyoV kinetic pathways. For simplicity, the nucleotide-free state, following ADP release from the TH and before ATP binding, is not shown. (D) Probability of each kinetic pathway as a function of backward force F (with ) calculated from the theory using the parameter set in Table 1.