Fig. 1.

(A) Detection and evaluation of A549-luc-C8 metastatic lung cancer growth in SCID-bg mice using a CCCD camera. Mice were treated once weekly for 4 wk (treatment days are indicated by arrows). Results are presented as the average total luminescence in radiance units (photons/s/cm²) ± SEM, n = 9. No significant difference (P > 0.05) of tumor growth at days 28, 42, 49, and 56 was observed between PBS and Taxotere groups, whereas an extremely significant difference (P < 0.0001) was noted between PBS and Taxotere groups compared with the docetaxel formulation. (B) Representative images of the total tumor luminescence in tumor bearing mice at day 42 after tumor cells inoculation and 35 d following treatments. (C) Survival rate analysis comparing treatment arms.