(A) Plasma docetaxel concentration–time profiles (±SD) obtained following oral administration of 10 mg/kg docetaxel MPs formulation to nontreated rats, n = 4, to cycloheximide-treated rats 1 h before administration, n = 2, and 1.5 h before administration, n = 4. (B) Plasma docetaxel concentration–time profiles following oral administration of docetaxel-NCs at a dose of 10 mg/kg to fasted rats, n = 5. The docetaxel NCs were prepared exactly as the NC of docetaxel formulation.