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. 2013 Sep 17;1(4):e00073. doi: 10.1002/phy2.73

Figure 3.

Figure 3

Serpina 1a, MUPs, and LCN2 gene expression changes determined by qPCR are consistent with microarray findings. (A) demonstrates a marked increase in Serpina 1a mRNA following CBDL in both strains. Also, there is a strain difference with increased Serpina 1a mRNA expression in B6 as compared to A/J mice. (B) demonstrates marked strain differences in MUP mRNA expression in the sham animals with disparate responses to CBDL. A/J sham MUP mRNA expression is low and expression increases following CBDL; whereas, in the B6 strain, MUP mRNA expression is very high in the sham group but falls in the CBDL group. (C) shows low expression of LCN2 mRNA in sham animals with marked increases following CBDL in both strains.