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. 2013 Sep 17;1(4):e00073. doi: 10.1002/phy2.73

Figure 6.

Figure 6

FITC-dextran permeability assay in Cdx2-IEC cells. Cells exposed to calcium-free (Ca-free) media resulted in a marked increase in cell permeability compared to Cdx2-IEC cells in control media (*P < 0.04). Cells treated with Control siRNA at 80 nmol/L and MUP-1 siRNA at 40 nmol/L concentrations were similar to untreated cells; whereas, cells treated with MUP-1 siRNA at 60 nmol/L concentration had significantly increased cell permeability compared to Cdx2-IEC cells in control media (**P < 0.0002). Indeed, permeability of cells treated with MUP-1 siRNA at 60 nmol/L concentration was similar to cells in calcium-free media.