Table I.
Group | MST | p-Value* |
---|---|---|
Concurrent (experiment 1) | ||
1 (Ara-C; n =5) | 19 | <0.05 |
2 (Combotox; n =5) | 20 | |
3 (Ara-C and Combotox; n =5) | 27 | |
4 (normal saline; n =5) | 17 | |
Sequential (experiment 2) | ||
1 (Ara-C; n =5) | 20 | <0.05† |
2 (Combotox; n =5) | 18 | |
3 (Ara-C and Combotox; n =5) | 28 | |
4 (normal saline; n =5) | 19 | |
Concurrent vs. sequential (experiment 3) | ||
1 (Ara-C and Combotox concurrent; n =8) | 22 | <0.001 |
2 (Ara-C and Combotox sequential; n =8) | 36 | |
3 (normal saline; n =8) | 28 |
p-Value calculated for overall survival difference with two-sided log-rank test.
p-Value for survival analysis calculated excluding mice that died accidentally on day of facial vein blood draw (two per group). If these mice were included, p-value would be 0.13.