Table 4.
Comparisons between CSF and serum cytokine levels
| Cytokine | CSF/serum correlation r2 | CSF/serum correlation P | MWU CSF vs serum | Location of higher concentration |
|---|---|---|---|---|
| IL-1b | 0.006 | 0.65 | <0.0001 | SERUM |
| IL-2 | U | U | U | CSF |
| IL-4 | 0.00002 | 0.98 | 0.0002 | SERUM |
| IL-6 | 0.021 | 0.41 | 0.55 | - |
| IL-8 | 0.043 | 0.25 | <0.0001 | CSF |
| IL-10 | 0.0008 | 0.88 | 0.15 | - |
| IL-12p70 | 0.093 | 0.08 | 0.44 | - |
| IL-17 | U | U | U | CSF |
| IL-22 | U | U | U | SERUM |
| IL-23 | U | U | U | - |
| IFNγ | 0.006 | 0.67 | <0.0001 | SERUM |
| TNFα | 0.0007 | 0.88 | 0.0003 | SERUM |
CSF/serum correlations: r2 column indicates the r2 value for the CSF and serum values; CSF/serum correlation p value column gives the p value for this correlation. MWU CSF vs serum indicates the Man Whitney U test p value of the comparison of the serum and CSF cytokine concentrations, with the body fluid in which the concentration was higher given in the neighboring column. “U” indicates that statistical analysis could not be done due to undetectable levels in one or more medium.