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Three of four possible MOG subsurface dimers are illustrated. The dimers’ accessibility hinges upon disruption of the myelin (oligodendrocyte) surface and thus exposing the relevant dimer target epitopes. The dimers’ estimated inter-epitope interval distances are, respectively, 8, 9, and 10 Ångströms, with each having KTGQF as a common target epitope. The potential dimers are KTGQF–NLHRT, KTGQF–LHRTF, and KTGQF–HRTFE.
