Figure 5.

The population of Tregs expands differently in allogeneic and syngeneic pregnancies. Foxp3^GFP mice were paired with C57/BL6 or BALB/c males and the expression of Foxp3^GFP+ was analyzed in the CD4⁺ cell population in the uterine draining lymph nodes (A and C) and thymus (B and D) on day 5 of pregnancy (d5). The same procedure was done with C57/BL6 females and the population of CD4⁺Foxp3⁺ cells was analyzed on day 10 of pregnancy (d10) (A-D). (n=5) A and B shows representative dot plots of the analyzed frequency of Foxp3⁺ in the gated population of CD4⁺ cells from one animal representative of each group. Data are expressed as single dots with medians and were analyzed by using the Mann-Whitney-U test (**: P ≤0.01).