Table 1.
Demographic data, risk factors, and serum Hcy, vitamin B12, and folate levels in the cases and controls
| Cases (n=171) | Controls (n=86) | P value | |
|---|---|---|---|
| Mean age, yr (±SD) | 67.9 (13.3) | 68.7 (8.4) | 0.607 |
| Gender, n (%) | |||
| Male | 74 (43.3) | 35 (40.7) | 0.789 |
| Female | 97 (56.7) | 51 (59.3) | |
| Diabetes mellitus, n (%) | |||
| No | 125 (73.1) | 62 (72.1) | 0.883 |
| Yes | 46 (26.9) | 24 (27.9) | |
| Hypertension, n (%) | |||
| No | 67 (39.2) | 61 (70.9) | <0.001 |
| Yes | 104 (60.8) | 25 (29.1) | |
| Hyperlipidemia, n (%) | |||
| No | 124 (72.5) | 48 (55.8) | 0.011 |
| Yes | 47 (27.5) | 38 (54.2) | |
| Smoking, n (%) | |||
| No | 150 (87.7) | 74 (86.0) | 0.697 |
| Yes | 21 (22.3) | 12 (14.0) | |
| Homocysteine (μmol/L) | |||
| Median | 13.6 | 11.7 | 0.013 |
| (Range) | (3.8-54.1) | (7.0-31.9) | |
| Mean | 16.2 | 13.5 | |
| (95% CI) | (14.8-17.5) | (12.4-14.6) | |
| Vitamin B12 (pmol/L) | |||
| Median | 242.9 | 328.7 | 0.083 |
| (Range) | (62.0-1400) | (63.0-1100) | |
| Mean | 327.3 | 386.1 | |
| (95% CI) | (286.0-368.5) | (333.4-438.8) | |
| Folate (nmol/L) | |||
| Median | 6.00 | 6.35 | 0.908 |
| (Range) | (2.7-18.0) | (2.90-15.30) | |
| Mean | 6.52 | 6.56 | |
| (95% CI ) | (6.12-6.92) | (6.06-7.05) |