Table 2.
Cell variable | PreD1 saline nare | PreD1 LPS nare | PostD1 saline nare | PostD1 LPS nare | PostD3 saline nare | PostD3 LPS nare |
---|---|---|---|---|---|---|
TCC/mg | 70 (18) | 231 (150) | 72 (21)+ | 201 (43)+ | 213 (83) | 147 (35) |
PMN/mg | 18 (12) | 15 (8)# | 37 (15)* | 136 (38)*,# | 175 (79) | 82 (23) |
Mac/mg | 26 (9) n = 9 | 10 (4) n = 8 | 7 (4) n = 5 | 11 (5) n = 8 | 5 (2) n = 7 | 14 (6) n = 8 |
TCC/mg, total cell counts per mg sputum; PMN/mg, polymorphonuclear neutrophils per mg sputum; Mac/mg, macrophage per mg sputum.
Significantly higher PMN in LPS nare compared with saline nare after Day 1 challenge (p = 0.001).
Significantly higher PMN in LPS nare after Day 1 challenge compared with baseline same nare (p = 0.002).
Significantly higher TCC in LPS nare compared with saline nare after Day1 challenge (p < 0.05).