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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Pharm Sci. 2013 Jul 29;102(10):10.1002/jps.23682. doi: 10.1002/jps.23682

Figure 3.

Figure 3

Simulated pharmacokinetic profiles of exenatide. A) Free exenatide and drug-receptor complex profiles following continuous SC infusion (20 µg/kg/day). Symbols are mean measured concentrations (±SD), and lines are model-predicted profiles. B) Free exenatide and drug-receptor complex profiles following multiple SC injections (10 µg/kg twice daily). C) Cumulative AURC during 2-week exenatide therapy. Solid line is simulation of AURC following continuous SC infusion and dashed line is simulated AURC following multiple SC injections.