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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Psychopharmacology (Berl). 2013 Feb 8;227(4):10.1007/s00213-013-2997-9. doi: 10.1007/s00213-013-2997-9

Fig 4.

Fig 4

Event-Related Spectral Perturbation (ERSP) in WT, Akt1+/− and Akt1−/− mice. Figure A Top shows response following saline while Figure A Bottom shows response following 50 mg/kg ketamine. B. Quantification and analysis of ERSP response during saline treatment revealed a lasting post stimulus suppression of theta power, and this did not differ as a function of genotype. Ketamine significantly reduced post stimulus suppression in all groups but had a significantly greater effect in mutant mice (all p<0.05). C. A significant decrease in gamma power was observed following ketamine administration, but this did not differ as a function of genotype (p<0.05). Asterisk depicts significance at p<0.05