Figure 10.
Some of the first 3-D MRSI data obtained with 1-D EPSI and 2 directions of phase encoding from a patient with prostate cancer. The left-most color overlay a) is the profile of the dual 1H/13C endorectal coil used for reception of the signals, the middle overlay b) is of pyruvate and the right most c) is of lactate. The reference image d) and spectral array e) show a portion of the 3D array that covers the tumor region. The voxels highlighted in red have lactate/pyruvate ratio that is indicative of tumor. The acquisition time for this 3D array was 12s, the matrix was 18×8×8 with a 7mm spatial resolution, a progressive flip angle, TE/TR=3/85-125ms, starting at 28s after the end of the injection of a dose of 0.43mL/Kg of hyperpolarized pyruvate.