Table 9.
HTS and Bisubstrate Inhibitors of PanC
| compound | IC50 (μM) | ||
|---|---|---|---|
| 141 |
|
75.0 | |
|
| |||
| 142 |
|
||
| 143 | |||
| 144 | |||
| 145 | |||
| 146 | |||
| 147 | |||
| 148 | |||
|
| |||
| 149 |
|
0.22 | |
| 150 |
|
|
4.0 |
| 151 | 18.0 | ||
HTS and Bisubstrate Inhibitors of PanC
| compound | IC50 (μM) | ||
|---|---|---|---|
| 141 |
|
75.0 | |
|
| |||
| 142 |
|
||
| 143 | |||
| 144 | |||
| 145 | |||
| 146 | |||
| 147 | |||
| 148 | |||
|
| |||
| 149 |
|
0.22 | |
| 150 |
|
|
4.0 |
| 151 | 18.0 | ||