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. Author manuscript; available in PMC: 2013 Oct 28.

Published in final edited form as: Pharm Res. 2009 Jun 25;26(9):10.1007/s11095-009-9923-1. doi: 10.1007/s11095-009-9923-1

Table IV. Diffusion Coefficients of Model Compounds in sIPNs and PEG-only Hydrogels at 37°C.

Solute	Type of loading	D (×10⁻⁸cm²/s)

		Early-time (0–6 h)						Late-time (6–24 h)

		1^a	2^a	3^a	4^a	5^a	6^a	1^a	2^a	3^a	4^a	5^a	6^a
AgSD	Single	1.760	1.680	1.640	1.670	2.640	0.972	1.647	0.987	0.745	1.869	3.307	1.112
AgSD	Concurrent	2.900	2.026	2.052	1.540	1.170	0.645	0.642	0.888	0.812	1.228	0.494	0.325
Bup	Single	4.250	3.829	3.649	4.180	4.620	2.75	1.480	0.787	0.895	2.480	1.534	0.096
Bup	Concurrent	4.394	3.841	3.878	4.080	3.950	2.12	1.38	1.20	0.827	1.193	2.028	0.094
NaSD	Single	2.560	2.560	1.530	-	-	3.18	1.13	1.19	0.675	-	-	1.6
KGF	Single	0.060	0.005	0.001	0.085	0.092	0.001	7.1 ×10⁻³	5.2×10⁻³	3.9×10⁻³	0.018	5.1 ×10⁻³	1.2×10⁻³
BSA-FITC	Single	0.333	0.234	0.155	0.412	1.310	0.63	0.155	0.131	0.110	0.225	0.331	0.23

^a

sIPN of gelatin/PEGdA w/w: 1, 10:15; 2, 10:20; 3, 10:30; 4, 15:15; 5, 20:15. 6, PEG-only hydrogel of 15% w/v PEGdA.