. Author manuscript; available in PMC: 2013 Oct 28.

Published in final edited form as: Pharm Res. 2009 Jun 25;26(9):10.1007/s11095-009-9923-1. doi: 10.1007/s11095-009-9923-1

Table VI. Regression Results of Diffusion Models Applied to Solute Diffusion in sIPN.

Solute	Type of loading	Early-time (0–6 h)							Late-time (6–24 h)

		Lustig-Peppas			Cukier		Ogston		Lustig-Peppas			Cukier

		k₁	k₂	R²	k_c	R²	r_f (Å)	R²	k₁	k₂	R²	k_c	R²	r_f (Å)	R²
(A) Varying PEGdA weight percentage
AgSD	Single	0	0.28	0.8966	2.07	0.9733	1.41	0.9884	0	0.28	0.9590	2.06	0.9595	1.39	0.9701
AgSD	Concurrent	0	0.26	0.9086	1.96	0.9796	1.32	0.9923	0	0.32	0.8850	2.36	0.9663	1.63	0.9835
Bup	Single	0	0.35	0.9021	2.17	0.9762	1.46	0.9903	0	0.45	0.9097	2.79	0.9798	1.92	0.9921
Bup	Concurrent	0	0.35	0.8997	2.16	0.9751	1.45	0.9896	0	0.45	0.9180	2.75	0.9837	1.90	0.9949
NaSD	Single	0	0.45	0.8380	2.70	0.9505	1.82	0.9806	0	0.52	0.8383	3.09	0.9512	2.11	0.9811
KGF	Single	0	0.05	0.9723	1.18	0.9965	0.84	0.9920	0	0.05	0.9098	1.19	0.9800	0.85	0.9927
BSA-FITC	Single	0	0.01	0.9298	0.37	0.9890	0.25	0.9976	0	0.01	0.9092	0.41	0.9797	0.28	0.9925
(B) Varying gelatin weight percentage
AgSD	Single	0	0.29	0.8666	2.14	0.9557	1.47	0.9758	0	0.21	0.8254	1.57	0.9188	1.03	0.9383
AgSD	Concurrent	0	0.30	0.8503	2.22	0.9453	1.53	0.9678	0	0.34	0.8132	2.53	0.9226	1.77	0.9495
Bup	Single	0	0.36	0.8676	2.23	0.9569	1.50	0.9769	0	0.42	0.5084	2.80	0.6798	1.97	0.7326
Bup	Concurrent	0	0.37	0.8520	2.30	0.9477	1.56	0.9699	0	0.55	0.7507	3.50	0.8776	2.48	0.9111
NaSD	Single	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KGF	Single	0	0.05	0.6729	1.07	0.7969	0.74	0.8518	0	0.06	0.8018	1.33	0.9005	0.94	0.9390
BSA-FITC	Single	0	0.01	0.8042	0.34	0.9086	0.22	0.9443	0	0.01	0.8380	0.41	0.9318	0.27	0.9059

Data represented as the average of three replicate studies.