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. Author manuscript; available in PMC: 2013 Oct 28.
Published in final edited form as: J Cutan Pathol. 2013 Feb 11;40(4):10.1111/cup.12090. doi: 10.1111/cup.12090

Fig. 4.

Fig. 4

A and B) Prurigo nodule. A) Psoriasiform acanthosis, vertical collagen streaks in dermal papillae and compact parakeratosis. Hematoxylin/eosin (H&E) sections, magnification ×40. B) Three mitotic figures are present in one high-power field (HPF; all normal bipolar). Some crowding is seen in the basal layer. Nuclear-cytoplasmic ratio of cells is not increased (<1 : 1) and irregular nuclei (sharply angulated nuclei) are not present. H&E sections, magnification ×600. C and D) Bowen’s disease. C) H&E sections, magnification ×100. D) Three mitotic figures are present in one HPF: one is abnormal and tripolar (right-sided arrow) and two are normal bipolar (left-sided arrow). Crowding is present in all epidermal layers. Cells have high N/C ratio (>1 : 1). H&E sections, magnification ×600.