Table-IV.
The diagnostic characteristics of EBV DNA in plasma and serum
| Subgroup | TP | FP | FN | TN | Pooled Sensitivity | Pooled Specificity | Pooled +LR(95% CI) | Pooled -LR(95% CI) | SROC |
|---|---|---|---|---|---|---|---|---|---|
| High quality of studies | |||||||||
| EBV-DNA | 678 | 323 | 199 | 1756 | 0.77(0.74-0.80) | 0.85(0.83-0.86) | 5.54(2.25-9.16) | 0.16(0.07-0.37) | 0.93 |
| VCA-IgA | 246 | 67 | 83 | 264 | 0.75(0.69-0.79) | 0.80(0.75-0.84) | 6.94(0.43-111.52) | 0.25(0.13-0.47) | 0.89 |
| Low qu ality of studies | |||||||||
| EBV-DNA | 565 | 69 | 224 | 782 | 0.72(0.68-0.75) | 0.92(0.90-0.94) | 10.20(4.27-24.36) | 0.20(0.09-0.43) | 0.96 |
| VCA-IgA | 1439 | 393 | 266 | 2296 | 0.84(0.82-0.86) | 0.85(0.84-0.87) | 13.05(5.69-29.93) | 0.19(0.12-0.29) | 0.944 |