Effect of Decreased Waist Circumference on UAE was Modified by Baseline Metabolic Syndrome and Baseline UAE. Changes in UAE (95% CI) associated with a 1-SD decrease (6.6 cm) in waist circumference stratified by baseline metabolic syndrome and UAE tertile are shown. All models adjusted for age, site, African-American race, baseline systolic BP, current smoking, baseline ln(UAE), changes in protein intake and 24-hour urine phosphorus. P value<0.05 for both interactions (baseline metabolic syndrome and baseline UAE as a continuous variable) on change in waist circumference.