Table 2.

Colon-to-Vaginal Tissue Concentration Ratio

	Homogenate TFV		Homogenate TFV-DP		Total Cell TFV-DP		CD4+ Cells TFV-DP
Days	N>0	Median (IQR)	N>0	Median (IQR)	N>0	Median (IQR)	N>0	Median (IQR)
1	5	33.8 (6.8, 37.8)*	5	123.7 (8.4, 155.4)*	5	0.3 (0.1, 0.4)	2	19.2 (9.6, 28.8)
8	6	4.5 (0.9, 31.3)	5	1.7 (0.3, 2.8)	4	1.1 (0.8, 1.4)	2	0.2 (0.2, 0.2)
15	1	0.3	2	2.6 (2.5, 2.6)	4	0.3 (0.1, 0.5)*	1	0.2

Values are median (interquartile range [IQR]) except where N = 2 where minimum and maximum are shown, and where N = 1 where IQR is not shown; TFV, tenofovir; N>0, number of participants with complete non-zero value (above limits of assay quantitation) for both colon and vaginal drug concentration; TFV-DP, tenofovir diphosphate; ^*p < 0.05.