TABLE 1 .
Genes of altered expression in the suhB mutant compared to wild-type PAK
| Gene category and designation |
Gene | Gene function | Fold change (suhB/WT) |
P value |
|---|---|---|---|---|
| Type III secretion genes | ||||
| PA0044 | exoT | Exoenzyme T | 0.083214 | 0.000311 |
| PA1690 | pscU | Translocation protein in type III secretion | 0.193606 | 0.024589 |
| PA1703 | pcrD | Type III secretory apparatus protein PcrD | 0.356385 | 0.010725 |
| PA1705 | pcrG | Regulator in type III secretion | 0.434703 | 0.008231 |
| PA1706 | pcrV | Type III secretion protein PcrV | 0.254249 | 0.008856 |
| PA1708 | popB | Translocator protein PopB | 0.107812 | 0.005814 |
| PA1709 | popD | Translocator outer membrane protein PopD precursor | 0.101252 | 0.00077 |
| PA1712 | exsB | Exoenzyme S synthesis protein B | 0.644707 | 0.00472 |
| PA1719 | pscF | Type III export protein PscF | 0.134511 | 0.000649 |
| PA1725 | pscL | Type III secretion system protein | 0.122295 | 0.001139 |
| PA2191 | exoY | Adenylate cyclase | 0.361816 | 0.009486 |
| PA3841 | exoS | Exoenzyme S | 0.028808 | 4.12E-07 |
| PA3842 | spcS | Chaperone | 0.231546 | 0.027402 |
| Flagellum biogenesis genes | ||||
| PA1077 | flgB | Flagellar basal body rod protein FlgB | 0.218089 | 0.007676 |
| PA1080 | flgE | Flagellar hook protein FlgE | 0.219233 | 0.004098 |
| PA1082 | flgG | Flagellar basal body rod protein FlgG | 0.2187 | 0.009148 |
| PA1088 | Hypothetical protein | 0.180182 | 0.005874 | |
| PA1092 | fliC | Flagellin type B | 0.217321 | 0.007287 |
| PA1104 | fliI | Flagellum-specific ATP synthase | 0.383827 | 0.009766 |
| Type VI secretion genes | ||||
| PA0070 | tagQ1 | Membrane proteins; protein secretion/export apparatus | 0.31983 | 0.043719 |
| PA0079 | tssK1 | Protein secretion/export apparatus | 10.6766 | 0.000804 |
| PA0080 | tssJ1 | Protein secretion/export apparatus | 7.66824 | 0.004379 |
| PA0088 | tssF1 | Protein secretion/export apparatus | 11.89032 | 0.005502 |
| PA0090 | clpV1 | ClpV1 protein | 2.022019 | 0.009987 |
| PA0091 | vgrG1 | VgrG1 | 45.37001 | 0.009213 |
| Pyocin synthesis genes | ||||
| PA0613 | Hypothetical protein | 0.209161 | 0.031819 | |
| PA0614 | Hypothetical protein | 0.138015 | 0.021263 | |
| PA0622 | Bacteriophage protein | 0.079474 | 3.87E-05 | |
| PA0623 | Bacteriophage protein | 0.109028 | 0.000165 | |
| PA0624 | Hypothetical protein | 0.100469 | 8.56E-05 | |
| PA0625 | Hypothetical protein | 0.142139 | 0.00168 | |
| PA0626 | Hypothetical protein | 0.186657 | 0.005785 | |
| PA0633 | Hypothetical protein | 0.065348 | 1.20E-05 | |
| PA0634 | Hypothetical protein | 0.22264 | 0.008216 | |
| PA0635 | Hypothetical protein | 0.162455 | 0.009963 | |
| PA0636 | Hypothetical protein | 0.149172 | 0.002497 | |
| PA0638 | Bacteriophage protein | 0.154734 | 0.001363 | |
| PA0639 | Hypothetical protein | 0.12724 | 0.000413 | |
| PA0641 | Bacteriophage protein | 0.297345 | 0.049771 | |
| PA0643 | Probable bacteriophage protein | 0.248638 | 0.015289 | |
| PA0984 | Colicin immunity protein | 0.062835 | 3.68E-06 | |
| PA0985 | pyoS5 | Pyocin S5 | 0.228836 | 0.016219 |