Figure 3.

Genomic context of selected genes for proteins involved in replication in archaea. Homologous genes are shown by arrows of the same color; genes are shown approximately to scale. (Blue) Replication genes; (magenta) genes coding for chromatin-binding protein and the respective modification enzymes; (orange) genes for translation system components; (gray) uncharacterized genes. Genes for which the neighborhood is discussed in the text are marked by an outline. The arCOG numbers to which uncharacterized proteins are assigned are shown in parentheses. HTH, helix–turn–helix domain; S7, ribosomal protein S7; CC1, DNA-binding protein CC1; Endo V, homolog of endonuclease V; Znf, Zn finger; TFIIB, transcription initiation factor TFIIB; HIT, HIT family hydrolase; MPP, metallophosphatase superfamily protein; HHT1, histone.