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. 2013 Aug 12;140(1):70–77. doi: 10.1111/imm.12111

Figure 1.

Figure 1

Interleukin-33 (IL-33) and ST2 are the early induced genes in colonic tissue of colitic mice. (a) Genespring GX11 analysis of Affymetrix Gene-Chip Expression Data (GSE22307) from the colonic tissue of dextran sulphate sodium (DSS) -induced colitis on Days 0, 2, 4 and 6, respectively, in mice. The differentially expressed cytokines and chemokines and genes implicated in the regulation of inflammation has been obtained from the hierarchical clusters and displayed as Box Plots (Fig. S1). (b) In vitro IL-33 protein levels in cultured colonic tissues from mice five or 6 days after DSS or PBS administration, respectively.