Table 1.

Summary of Zimmerman Program plasma VWF levels in healthy control subjects.

	All controls (n=232)			Caucasian (n=150)			African American (n=66)
	Mean	Median	Normal range	Mean	Median	Normal range	Mean	Median	Normal range
VWF:Ag	112	102	52–210	108	97	53–192	127	118	64–313
VWF:RCo	99	93	46–190	99	99	46–185	103	93	45–210
VWF:RCo/VWF:Ag ratio	0.91	0.90	0.60–1.37	0.94	0.95	0.67–1.38	0.82	0.81	0.51–1.23
FVIII	107	102	54–177	103	99	53–176	123	121	67–187
VWF:CB (type III)	133	122	57–266	127	117	55–250	152	145	71–296
VWF:CB/VWF:Ag ratio (type III)	1.19	1.18	0.87–1.50	1.17	1.16	0.86–1.48	1.21	1.24	0.88–1.54
VWF:CB (type I)	146	137	61–297	138	131	61–268	174	153	45–210
VWF:CB/VWF:Ag ratio (type I)	1.31	1.29	0.86–1.92	1.29	1.27	0.89–1.80	1.38	1.39	0.77–1.99
VWF:CB (type VI)	135	121	55–280	130	118	53–268	154	135	64–313
VWF:CB/VWF:Ag ratio (type VI)	1.21	1.21	0.76–1.65	1.21	1.21	0.74–1.66	1.21	1.21	0.80–1.61

Data were log-transformed to obtain a normal distribution. Geometric means are given for VWF:Ag, VWF:RCo, FVIII, and VWF:CB and arithmetic means for the VWF:CB/VWF:Ag ratios. Normal range is the mean ± 2 SD. Data are given in IU/dL with the exception of type VI collagen binding, which was normalized to an international standard and is given in U/dL.