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. Author manuscript; available in PMC: 2014 Oct 7.
Published in final edited form as: Mol Pharm. 2013 Aug 30;10(10):10.1021/mp4003688. doi: 10.1021/mp4003688

Figure 4.

Figure 4

a) Uptake of FITC-labeled nanogel and LHRH-nanogels by A2780 and SKOV-3 cells (3 h, 37°C, 0.1 mg/ml). b) Whole-cell Pt accumulation in A2780 and SKOV-3 cells as measured by ICP-MS (24 h, 37°C, > 0.5 mg/ml). c) Confocal micrographs (×63) of nanogel and LHRH-nanogel in A2780 cells. The cells were treated for 3 h with the FITC-labeled nanogels (green), stained with Hoechst 33342 (blue) for nucleus for 10 min at 37°C, followed by live cell imaging. Data are mean ± SD, n = 3, *p < 0.05, NS is not significant.