Figure 3. Itch is dispensable for Treg cell homeostasis.

(A) Percentages of YFP⁺ Treg cells among CD4⁺ T cells from spleen, peripheral lymph nodes (pLN), mesenteric lymph nodes (mLN), thymus, and colon of Itch^fl/flFoxp3^Cre and Itch^+/+Foxp3^Cre mice. (B) Frequency of YFP⁺ cells among CD4⁺ cells in the spleens of Itch^fl/flFoxp3^Cre and Itch^+/+Foxp3^Cre mice. (C) Absolute number of YFP⁺CD4⁺ cells in the spleen. Data represent the mean ± SEM. *P < 0.05 (unpaired 2-tailed Student’s t test).