Fig. 3.

Curcumin enhances cisplatin efficacy. MPM cells were either untreated (denoted as NT), treated with different concentrations of cisplatin (cis) for 24 h, or pretreated with noted doses of curcumin for 24 h followed by addition of indicated concentrations of cisplatin for further 24 h. Determination of viable/live cells was carried out by MTT assay as detailed in methods. Columns in each of the histograms represent means of 3–4 independent experiments; bars, S.E. * and @ significantly different from NT, P = <0.03 and <0.002, respectively