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Inhibition of platelet aggregation (final-extent, collagen-induced) following the administration of (a) ticagrelor at 50 mg bid for 5 days, and 200 mg bid for 4 days then qd for 1 day, ± once-daily aspirin (300 mg) (Study A), and (b) ticagrelor (200 mg bid for 5 days then a single 200 mg dose for 1 day) + aspirin (75 mg qd) and clopidogrel (loading dose 300 mg on Day 1 then 75 mg qd for 5 days) + aspirin (75 mg qd) (Study B). Values are mean ± SD.
