Figure 4.
Manhattan plots summarizing results of GWAS in two canine hereditary retinal degenerations, crd1 and crd2. x-axis = Canine chromosomes 1-38, plus the X-chromosome presented as chromosomes 39 or 39 and 41. Y-axis = probability statistic (−log10[observed P]). (A) crd1. Results of association analysis using PLINK software. The highest −log10(P) values are observed at the telomeric end of chromosome 3 (CFA3). The X chromosome is represented by number 39 and 41. (B) crd2. Results of association analysis using Fisher-exact test. The highest peak is observed on chromosome 33. A second peak at lower significance is observed on CFA12. The X chromosome is represented by the numbers 39 and 40.