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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: ChemMedChem. 2012 Dec 13;8(2):10.1002/cmdc.201200422. doi: 10.1002/cmdc.201200422

Figure 3.

Figure 3

Surface Plasmon Resonance analyzed effects of peptides UM-24, KR-41 and KR-42 on a) sCD4 and b) mAb 17b interactions with HIV-1YU-2 gp120. Results are given as the percentage of gp120 bound relative to gp120 bound in the absence of peptide: 100 × [(RU−RUgp120)/RUgp120]. The normalized values were plotted in Origin7 to get IC50 values. The IC50 values were 45.0 nM, 30 nM and 118.77 nM for UM-24, KR-41 and KR-42 respectively for sCD4 inhibition. The IC50 values were 71.5 nM, 50.8 nM and 207.8 nM for UM-24, KR-41 and KR-42 respectively for mAb 17b inhibition.