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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Hypertens Rep. 2013 Oct;15(5):10.1007/s11906-013-0383-y. doi: 10.1007/s11906-013-0383-y

Figure 3.

Figure 3

Effects of cAMP-dependent protein kinase A- or phospholipase C-selective inhibitors on glucagon-induced MAP kinases ERK 1/2 phosphorylation in rat glomerular mesangial cells. Both H-89 and U73122 blocked the effects of glucagon on MAP kinases ERK 1/2 phosphorylation. (A) Western blot of phosphorylated and total ERK 1/2; (B) quantitative changes in phosphorylated ERK 1/2 from control. **p<0.01 vs control; ++p<0.01 vs glucagon. Reprinted with permission from Li et al. [35]. Glucagon receptor-mediated ERK 1/2 phosphorylation in rat mesangial cells: role of protein kinase A and phospholipase C. Hypertension 2006; 47, 1–6.