Table 6.

Predictive performance of the newly created clinicopathologic Leuven donor risk score

Score	Algorithm Obtained from Logistic Regression Analysis on Historic Cohort	Historic Cohort		Validation Cohort
		AUC under ROC Curve	P	AUC under ROC Curve	P
1 (3-yr prediction)	Age + 2 GS + 10 IFTA	0.65	0.03	0.70	0.01
2 (Leuven donor risk score; 5-yr prediction)	GS + 3 IFTA + age	0.67	0.002	0.81	<0.001
3 (10-yr prediction)	1.5 age + 14 GS + IFTA	0.60	0.05	–	–

Logistic regression analysis was performed on the historic cohort (n=181 for 3- and 5-year survival; n=124 for 10-year survival) to construct a predictive algorithm for graft survival at 3, 5, and 10 years after transplantation. This algorithm was then applied to the validation cohort (n=367 for 3-year survival; n=145 for 5-year survival). gs, glomerulosclerosis score (gs <10%=0; gs >10%=1); ifta, interstitial fibrosis/tubular atrophy grade according to Banff classification.