Table 1.
Baseline characteristics of the study sample
| Characteristic | Overall |
|---|---|
| N | 2948 |
| Mean age, yr | 59 (10) |
| Women | 53 (1561) |
| Mean BMI, kg/m2 | 28.0 (5.2) |
| Mean systolic BP, mmHg | 128 (19) |
| Hypertension | 40.7 (1199) |
| Diabetes | 9.4 (278) |
| HDL cholesterol, mg/dl | 51 (16) |
| Triglycerides, mg/dla | 117 (82, 171) |
| CKD | 8.9 (261) |
| Mean eGFR, ml/min per 1.73 m2 | 87 (25) |
| Albuminuria | 17.5 (517) |
| Median biomarker levels indexed to urinary creatinine (25th, 75th percentiles) | |
| α1-microglobulin, ng/ml | 5.0 (2.0, 20.0) |
| β2-microglobulin, ng/ml | 0.3 (0.05, 0.8) |
| Calbindin, ng/ml | 0.4 (0.08, 1.0) |
| Clusterin (Apolipoprotein J), ng/ml | 0.1 (0.01, 0.5) |
| CTGF, pg/ml | 5.0 (2.0,10.0) |
| Cystatin-C, ng/ml | 0.08 (0.01, 0.2) |
| GST-α, pg/ml | 2.0 (1.0, 6.0) |
| Kim-1, pg/mL | 4.0 (2.0, 7.0) |
| NGAL, ng/ml | 0.1 (0.04, 0.4) |
| Osteopontin, ng/ml | 9.2 (5.2, 13.5) |
| TFF-3, ng/ml | 4.0 (2.0, 7.0) |
| Tamm–Horsfall Protein (uromodulin), μg/ml | 0.09 (0.04, 0.2) |
| Tissue inhibitor of matrix metalloproteinase-1, pg/ml | 9.0 (3.0, 20.0) |
| Vascular endothelial growth factor, pg/ml | 2.2 (1.01, 3.5) |
Data are shown as mean (SD) for continuous variables and percent (n) for categorical variables. Albuminuria was defined as a spot UACR of ≥17 mg/g in men and ≥25 mg/g in women.
a
Median (25th, 75th percentiles).