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ABIN1[D485N] knockin mice develop progressive GN. (A and B) Graphical representations of the data in Table 1 showing that ABIN1[D485N] mice develop progressive glomerular and interstitial injury compared with WT mice. (C) Urine albumin-to-creatinine ratio of 3- to 4-month-old and 5- to 6-month-old ABIN1[D485N] and WT mice (total n=82). (D) Serum complement factor 3 (C3) levels for the same groups. All P values were calculated using the Mann-Whitney rank-order test.
